产品名称
SRPX2 Rabbit Polyclonal Antibody
蛋白名称
Sushi repeat-containing protein SRPX2
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=27286
Human Swissprot No.
O60687
Human Swissprot Link
https://www.uniprot.org/uniprot/O60687
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=68792
Mouse Swissprot No.
Q8R054
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8R054/entry
特异性
This antibody detects endogenous levels of SRPX2 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in neurons of the rolandic area of the brain (at protein level). Highly expressed in the brain, placenta, lung, trachea, uterus, adrenal gland, heart, ovary and placenta. Weakly expressed in the peripheral blood, brain and bone marrow. Expressed in numerous cancer cell lines and in gastrointestinal cancer cells. Higher levels found in colorectal cancers than in normal colonic mucosa.
细胞定位
Secreted. Cytoplasm. Cell surface. Cell junction, synapse .
功能
Acts as a ligand for the urokinase plasminogen activator surface receptor. Plays a role in angiogenesis by inducing endothelial cell migration and the formation of vascular network (cords). Involved in cellular migration and adhesion. Increases the phosphorylation levels of FAK. Interacts with and increases the mitogenic activity of HGF. Promotes synapse formation. May have a role in the perisylvian region, critical for language and cognitive development.
