产品名称
GPR177 Rabbit Polyclonal Antibody
基因名称
WLS C1orf139 GPR177 UNQ85/PRO18667
蛋白名称
Protein wntless homolog (Integral membrane protein GPR177) (Protein evenness interrupted homolog) (EVI) (Putative NF-kappa-B-activating protein 373)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=79971
Human Swissprot No.
Q5T9L3
Human Swissprot Link
https://www.uniprot.org/uniprot/Q5T9L3
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=68151
Mouse Swissprot No.
Q6DID7
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q6DID7/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=362065
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q6P689/entry
特异性
This antibody detects endogenous levels of GPR177 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Golgi apparatus membrane ; Multi-pass membrane protein . Cytoplasmic vesicle membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . Endoplasmic reticulum membrane ; Multi-pass membrane protein . Golgi apparatus membrane ; Multi-pass membrane protein . Early endosome membrane ; Multi-pass membrane protein . Co-localizes with the adaptin AP2A2 at distinct punctae. .
功能
Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins. Plays also an important role in establishment of the anterior-posterior body axis formation during development (By similarity).
