产品名称
SFTPD Rabbit Polyclonal Antibody
基因名称
SFTPD COLEC7 PSPD SFTP4
蛋白名称
Pulmonary surfactant-associated protein D (PSP-D) (SP-D) (Collectin-7) (Lung surfactant protein D)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P35247
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P35247/entry
Mouse Swissprot No.
P50404
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P50404
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P35248
免疫原
Synthesized peptide derived from human protein . at AA range: 290-370
特异性
SFTPD Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is part of the innate immune response, protecting the lungs against inhaled microorganisms and chemicals. The encoded protein may also be involved in surfactant metabolism. [provided by RefSeq, Jul 2015],
组织表达
Expressed in lung, brain, pancreas and adipose tissue (mainly mature adipocytes).
细胞定位
Secreted, extracellular space, extracellular matrix. Secreted, extracellular space, surface film.
功能
function:Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.,miscellaneous:Pulmonary surfactant consists of 90% lipid and 10% protein. There are 4 surfactant-associated proteins: 2 collagenous, carbohydrate-binding glycoproteins (SP-A and SP-D) and 2 small hydrophobic proteins (SP-B and SP-C).,online information:Pulmonary surfactant protein SP-D,PTM:Hydroxylation on proline residues within the sequence motif, GXPG, is most likely to be 4-hydroxy as this fits the requirement for 4-hydroxylation in vertebrates.,PTM:The N-terminus is blocked.,similarity:Belongs to the SFTPD family.,similarity:Contains 1 C-type lectin domain.,similarity:Contains 1 collagen-like domain.,subunit:Oligomeric complex of 4 set of homotrimers.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
