产品名称
SEC24A Rabbit Polyclonal Antibody
蛋白名称
Protein transport protein Sec24A (SEC24-related protein A)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10802
Human Swissprot No.
O95486
Human Swissprot Link
https://www.uniprot.org/uniprot/O95486
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=77371
Mouse Swissprot No.
Q3U2P1
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q3U2P1/entry
特异性
This antibody detects endogenous levels of SEC24A at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Cytoplasmic vesicle, COPII-coated vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Endoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasm, cytosol .
功能
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex . Plays a central role in cargo selection within the COPII complex and together with SEC24B may have a different specificity compared to SEC24C and SEC24D. May package preferentially cargos with cytoplasmic DxE or LxxLE motifs and may also recognize conformational epitopes .
