产品名称
SRP68 Rabbit Polyclonal Antibody
蛋白名称
Signal recognition particle 68 kDa protein (SRP68)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6730
Human Swissprot No.
Q9UHB9
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9UHB9
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=217337
Mouse Swissprot No.
Q8BMA6
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BMA6/entry
特异性
This antibody detects endogenous levels of SRP68 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Cytoplasm . Nucleus, nucleolus . Endoplasmic reticulum .
功能
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) . The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER . The SRP complex targets the ribosome-nascent chain complex to the SRP receptor (SR), which is anchored in the ER, where SR compaction and GTPase rearrangement drive cotranslational protein translocation into the ER . Binds the signal recognition particle RNA (7SL RNA), SRP72 binds to this complex subsequently . The SRP complex possibly participates in the elongation arrest function (By similarity).
