产品名称
BT2A2 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/10385
Human Swissprot No.
Q8WVV5
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8WVV5/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/238555
Mouse Swissprot No.
A4QPC6
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/A4QPC6
免疫原
Synthesized peptide derived from human BT2A2 AA range: 325-375
特异性
This antibody detects endogenous levels of BT2A2 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
Butyrophilin is the major protein associated with fat droplets in the milk. This gene is a member of the BTN2 subfamily of genes, which encode proteins belonging to the butyrophilin protein family. The gene is located in a cluster on chromosome 6, consisting of seven genes belonging to the expanding B7/butyrophilin-like group, a subset of the immunoglobulin gene superfamily. The encoded protein is a type I receptor glycoprotein involved in lipid, fatty-acid and sterol metabolism. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010],
组织表达
Highly expressed in brain, bone marrow, small intestine, muscle, spleen and pancreas. Moderate expression was seen in lung, liver and kidney.
细胞定位
Membrane ; Single-pass type I membrane protein .
功能
similarity:Belongs to the immunoglobulin superfamily. BTN/MOG family.,similarity:Contains 1 B30.2/SPRY domain.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,tissue specificity:Highly expressed in brain, bone marrow, small intestine, muscle, spleen and pancreas. Moderate expression was seen in lung, liver and kidney.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
