产品名称
KCTD12 Rabbit Polyclonal Antibody
基因名称
KCTD12 C13orf2 KIAA1778 PFET1
蛋白名称
BTB/POZ domain-containing protein KCTD12 (Pfetin) (Predominantly fetal expressed T1 domain)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=115207
Human Swissprot No.
Q96CX2
Human Swissprot Link
https://www.uniprot.org/uniprot/Q96CX2
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=239217
Mouse Swissprot No.
Q6WVG3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q6WVG3/entry
特异性
This antibody detects endogenous levels of KCTD12 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Present in a variety of fetal organs, with highest expression levels in the cochlea and brain and, in stark contrast, is detected only at extremely low levels in adult organs, such as brain and lung.
细胞定位
Cell junction, synapse, presynaptic cell membrane. Cell junction, synapse, postsynaptic cell membrane .
功能
Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity).
