产品名称
SLC38A1 Rabbit Polyclonal Antibody
基因名称
SLC38A1 ATA1 NAT2 SAT1 SNAT1
蛋白名称
Sodium-coupled neutral amino acid transporter 1 (Amino acid transporter A1) (N-system amino acid transporter 2) (Solute carrier family 38 member 1) (System A amino acid transporter 1) (System N amino acid transporter 1)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=81539
Human Swissprot No.
Q9H2H9
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9H2H9
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=105727
Mouse Swissprot No.
Q8K2P7
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8K2P7/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=170567
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q9JM15/entry
特异性
This antibody detects endogenous levels of SLC38A1 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in the cerebral cortex by pyramidal and GABAergic neurons, astrocytes and other non-neuronal cells (at protein level). Expressed in placenta, heart, lung, skeletal muscle, spleen, stomach and testis.
细胞定位
Cell membrane ; Multi-pass membrane protein . Restricted to the somatodendritic compartment of neurons. Found in the cellular processes of neurons in the developing brain (By similarity). .
功能
Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of glutamine and sodium ions with a stoichiometry of 1:1. May also transport small zwitterionic and aliphatic amino acids with a lower affinity. May supply glutamatergic and GABAergic neurons with glutamine which is required for the synthesis of the neurotransmitters glutamate and GABA.
