产品名称
CRAT Rabbit Polyclonal Antibody
蛋白名称
Carnitine O-acetyltransferase (Carnitine acetylase) (EC 2.3.1.7) (Carnitine acetyltransferase) (CAT) (CrAT)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1384
Human Swissprot No.
P43155
Human Swissprot Link
https://www.uniprot.org/uniprot/P43155
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=12908
Mouse Swissprot No.
P47934
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P47934/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=311849
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q704S8/entry
特异性
This antibody detects endogenous levels of CRAT at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Mostly in skeletal muscle, less in heart, liver and pancreas, only weakly detectable in brain, placenta, lung and kidney.
细胞定位
Endoplasmic reticulum . Peroxisome . Mitochondrion inner membrane ; Peripheral membrane protein ; Matrix side .; [Isoform 1]: Mitochondrion .; [Isoform 2]: Peroxisome .
功能
Catalyzes the reversible transfer of acyl groups from carnitine to coenzyme A (CoA) and regulates the acyl-CoA/CoA ratio. Also plays a crucial role in the transport of fatty acids for beta-oxidation . Responsible for the synthesis of short- and branched-chain acylcarnitines . Active towards some branched-chain amino acid oxidation pathway (BCAAO) intermediates . Trans-2-enoyl-CoAs and 2-methylacyl-CoAs are poor substrates .
