产品名称
EIF4A2 Rabbit Polyclonal Antibody
蛋白名称
Eukaryotic initiation factor 4A-II (eIF-4A-II) (eIF4A-II) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-2)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1974
Human Swissprot No.
Q14240
Human Swissprot Link
https://www.uniprot.org/uniprot/Q14240
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=13682
Mouse Swissprot No.
P10630
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P10630/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=303831
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q5RKI1/entry
特异性
This antibody detects endogenous levels of EIF4A2 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
