产品名称
OS9 Rabbit Polyclonal Antibody
蛋白名称
Protein OS-9 (Amplified in osteosarcoma 9)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10956
Human Swissprot No.
Q13438
Human Swissprot Link
https://www.uniprot.org/uniprot/Q13438
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=216440
Mouse Swissprot No.
Q8K2C7
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8K2C7/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=362891
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q5RKH6/entry
特异性
This antibody detects endogenous levels of OS9 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Ubiquitously expressed. Found as well in all tumor cell lines analyzed, amplified in sarcomas. Highly expressed in osteosarcoma SJSA-1 and rhabdomyosarcoma Rh30 cell lines. Isoform 2 is the major isoform detected in all cell types examined.
细胞定位
Endoplasmic reticulum lumen .
功能
Lectin which functions in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD). May bind terminally misfolded non-glycosylated proteins as well as improperly folded glycoproteins, retain them in the ER, and possibly transfer them to the ubiquitination machinery and promote their degradation. Possible targets include TRPV4.
