产品名称
Syntaxin 4 Rabbit Polyclonal Antibody
蛋白名称
Syntaxin-4 (Renal carcinoma antigen NY-REN-31)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6810
Human Swissprot No.
Q12846
Human Swissprot Link
https://www.uniprot.org/uniprot/Q12846
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=20909
Mouse Swissprot No.
P70452
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P70452/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=81803
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q08850/entry
特异性
This antibody detects endogenous levels of Syntaxin 4 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in neutrophils and neutrophil-differentiated HL-60 cells. Expression in neutrophils increases with differentiation.
细胞定位
Cell membrane ; Single-pass type IV membrane protein . Cell projection, neuron projection . Localizes to neurite tips in neuronal cells. .
功能
Plasma membrane t-SNARE that mediates docking of transport vesicles (By similarity). Necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane (By similarity). In neurons, recruited at neurite tips to membrane domains rich in the phospholipid 1-oleoyl-2-palmitoyl-PC (OPPC) which promotes neurite tip surface expression of the dopamine transporter SLC6A3/DAT by facilitating fusion of SLC6A3-containing transport vesicles with the plasma membrane (By similarity). Together with STXB3 and VAMP2, may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes and in docking of synaptic vesicles at presynaptic active zones (By similarity).
