产品名称
RMI1 Rabbit Polyclonal Antibody
蛋白名称
RecQ-mediated genome instability protein 1 (BLM-associated protein of 75 kDa) (BLAP75) (FAAP75)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=80010
Human Swissprot No.
Q9H9A7
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9H9A7
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=74386
Mouse Swissprot No.
Q9D4G9
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9D4G9/entry
特异性
This antibody detects endogenous levels of RMI1 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Nucleus . Forms foci in response to DNA damage.
功能
Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability.
