产品名称
GP73/GOLPH2 Rabbit Polyclonal Antibody
基因名称
GOLM1 C9orf155 GOLPH2 PSEC0242 UNQ686/PRO1326
蛋白名称
Golgi membrane protein 1 (Golgi membrane protein GP73) (Golgi phosphoprotein 2)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=51280
Human Swissprot No.
Q8NBJ4
Human Swissprot Link
https://www.uniprot.org/uniprot/Q8NBJ4
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=105348
Mouse Swissprot No.
Q91XA2
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q91XA2/entry
特异性
This antibody detects endogenous levels of GP73/GOLPH2 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Widely expressed. Highly expressed in colon, prostate, trachea and stomach. Expressed at lower level in testis, muscle, lymphoid tissues, white blood cells and spleen. Predominantly expressed by cells of the epithelial lineage. Expressed at low level in normal liver. Expression significantly increases in virus (HBV, HCV) infected liver. Expression does not increase in liver disease due to non-viral causes (alcohol-induced liver disease, autoimmune hepatitis). Increased expression in hepatocytes appears to be a general feature of advanced liver disease. In liver tissue from patients with adult giant-cell hepatitis (GCH), it is strongly expressed in hepatocytes-derived syncytial giant cells. Constitutively expressed by biliary epithelial cells but not by hepatocytes.
细胞定位
Golgi apparatus, cis-Golgi network membrane ; Single-pass type II membrane protein . Early Golgi. Cycles via the cell surface and endosomes upon lumenal pH disruption.
功能
Unknown. Cellular response protein to viral infection.
