产品名称
LSS Rabbit Polyclonal Antibody
蛋白名称
Lanosterol synthase (EC 5.4.99.7) (2,3-epoxysqualene--lanosterol cyclase) (Oxidosqualene--lanosterol cyclase) (OSC) (hOSC)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4047
Human Swissprot No.
P48449
Human Swissprot Link
https://www.uniprot.org/uniprot/P48449
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=16987
Mouse Swissprot No.
Q8BLN5
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BLN5/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=81681
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P48450/entry
特异性
This antibody detects endogenous levels of LSS at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Widely expressed. Expressed in the hair bulb, the outer root sheath and hair matrix of the hair follicle epithelium. Also detected in dermal papilla, epidermis, sweat glands, sebaceous glands, and blood vessels.
细胞定位
Endoplasmic reticulum membrane ; Peripheral membrane protein .
功能
Key enzyme in the cholesterol biosynthesis pathway. Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus . Through the production of lanosterol may regulate lens protein aggregation and increase transparency .
