产品名称
NSDHL Rabbit Polyclonal Antibody
蛋白名称
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating (EC 1.1.1.170) (Protein H105e3)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=50814
Human Swissprot No.
Q15738
Human Swissprot Link
https://www.uniprot.org/uniprot/Q15738
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=18194
Mouse Swissprot No.
Q9R1J0
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9R1J0/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=309262
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q5PPL3/entry
特异性
This antibody detects endogenous levels of NSDHL at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Brain, heart, liver, lung, kidney, skin and placenta.
细胞定位
Endoplasmic reticulum membrane ; Single-pass membrane protein . Lipid droplet . Trafficking through the Golgi is necessary for ER membrane localization. .
功能
Catalyzes the NAD(P)(+)-dependent oxidative decarboxylation of the C4 methyl groups of 4-alpha-carboxysterols in post-squalene cholesterol biosynthesis (By similarity). Plays also a role in the regulation of the endocytic trafficking of EGFR (By similarity).
