产品名称
CCDC93 Rabbit Polyclonal Antibody
蛋白名称
Coiled-coil domain-containing protein 93
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=54520
Human Swissprot No.
Q567U6
Human Swissprot Link
https://www.uniprot.org/uniprot/Q567U6
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=70829
Mouse Swissprot No.
Q7TQK5
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q7TQK5/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=304743
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q5BJT7/entry
特异性
This antibody detects endogenous levels of CCDC93 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Component of the CCC complex, which is involved in the regulation of endosomal recycling of surface proteins, including integrins, signaling receptor and channels. The CCC complex associates with SNX17, retriever and WASH complexes to prevent lysosomal degradation and promote cell surface recycling of numerous cargos such as integrins ITGA5:ITGB1 . Involved in copper-dependent ATP7A trafficking between the trans-Golgi network and vesicles in the cell periphery; the function is proposed to depend on its association within the CCC complex and cooperation with the WASH complex on early endosomes and is dependent on its interaction with WASHC2C . ; (Microbial infection) The CCC complex, in collaboration with the heterotrimeric retriever complex, mediates the exit of human papillomavirus to the cell surface.
