产品名称
Antizyme inhibitor 1 Rabbit Polyclonal Antibody
蛋白名称
Antizyme inhibitor 1 (AZI) (Ornithine decarboxylase antizyme inhibitor)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=51582
Human Swissprot No.
O14977
Human Swissprot Link
https://www.uniprot.org/uniprot/O14977
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=54375
Mouse Swissprot No.
O35484
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/O35484/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=58961
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q63764/entry
特异性
This antibody detects endogenous levels of Antizyme inhibitor 1 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Antizyme inhibitor (AZI) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (AZs) OAZ1, OAZ2 and OAZ3 on ODC activity by competing with ODC for antizyme-binding . Inhibits antizyme-dependent ODC degradation and releases ODC monomers from their inactive complex with antizymes, leading to formation of the catalytically active ODC homodimer and restoring polyamine production .
