产品名称
TEX10 Rabbit Polyclonal Antibody
蛋白名称
Testis-expressed sequence 10 protein
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=54881
Human Swissprot No.
Q9NXF1
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9NXF1
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=269536
Mouse Swissprot No.
Q3URQ0
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q3URQ0/entry
特异性
This antibody detects endogenous levels of TEX10 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Nucleus, nucleoplasm . Cytoplasm . Nucleus, nucleolus . Mainly found in the nucleoplasm, with low levels detected in the cytoplasmic and chromatin fractions. .
功能
Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes . Component of the PELP1 complex involved in the nucleolar steps of 28S rRNA maturation and the subsequent nucleoplasmic transit of the pre-60S ribosomal subunit .
