产品名称
ARL4C Rabbit Polyclonal Antibody
蛋白名称
ADP-ribosylation factor-like protein 4C (ADP-ribosylation factor-like protein 7) (ADP-ribosylation factor-like protein LAK)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10123
Human Swissprot No.
P56559
Human Swissprot Link
https://www.uniprot.org/uniprot/P56559
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=320982
Mouse Swissprot No.
P61208
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P61208/entry
特异性
This antibody detects endogenous levels of ARL4C at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in several tumor cell lines (at protein level). Expressed in lung, brain, leukocytes and placenta.
细胞定位
Cell projection, filopodium. Cell membrane. Cytoplasm.
功能
Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. May be involved in transport between a perinuclear compartment and the plasma membrane, apparently linked to the ABCA1-mediated cholesterol secretion pathway. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in the GDP-bound form. Regulates the microtubule-dependent intracellular vesicular transport from early endosome to recycling endosome process.
