产品名称
S10AD Rabbit Polyclonal Antibody
蛋白名称
Protein S100-A13 (S100 calcium-binding protein A13)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q99584
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q99584/entry
Mouse Swissprot No.
P97352
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P97352
免疫原
Synthesized peptide derived from human protein . at AA range: 10-90
特异性
S10AD Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is widely expressed in various types of tissues with a high expression level in thyroid gland. In smooth muscle cells, this protein co-expresses with other family members in the nucleus and in stress fibers, suggesting diverse functions in signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],
组织表达
Expressed in heart and skeletal muscle.
细胞定位
Cytoplasm. Secreted. Secretion is mediated by exposure to stress and requires copper ions.
功能
similarity:Belongs to the S-100 family.,similarity:Contains 2 EF-hand domains.,tissue specificity:Expressed in heart and skeletal muscle.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
