产品名称
PPME1 Rabbit Polyclonal Antibody
基因名称
PPME1 PME1 PP2593 PRO0750
蛋白名称
Protein phosphatase methylesterase 1 (PME-1) (EC 3.1.1.89)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9Y570
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Y570/entry
Mouse Swissprot No.
Q8BVQ5
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BVQ5
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q4FZT2
免疫原
Synthesized peptide derived from human protein . at AA range: 220-300
特异性
PPME1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a protein phosphatase methylesterase localized to the nucleus. The encoded protein acts on the protein phosphatase-2A catalytic subunit and supports the ERK pathway through dephosphorylation of regulatory proteins. It plays a role in malignant glioma progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012],
组织表达
Amygdala,Cervix carcinoma,Fetal liver,Lung,Platelet,Skin,
细胞定位
cell-cell adherens junction,
功能
function:Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro).,sequence caution:Wrong choice of CDS.,similarity:Belongs to the AB hydrolase superfamily.,subunit:Binds PPP2CB.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.