产品名称
MTHFD1 Rabbit Polyclonal Antibody
蛋白名称
C-1-tetrahydrofolate synthase, cytoplasmic (C1-THF synthase) [Includes: Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate synthetase (EC 6.3.4.3)]
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4522
Human Swissprot No.
P11586
Human Swissprot Link
https://www.uniprot.org/uniprot/P11586
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=108156
Mouse Swissprot No.
Q922D8
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q922D8/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=64300
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P27653/entry
特异性
This antibody detects endogenous levels of MTHFD1 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Trifunctional enzyme that catalyzes the interconversion of three forms of one-carbon-substituted tetrahydrofolate: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate, 5,10-methenyltetrahydrofolate and (6S)-10-formyltetrahydrofolate . These derivatives of tetrahydrofolate are differentially required in nucleotide and amino acid biosynthesis, (6S)-10-formyltetrahydrofolate being required for purine biosynthesis while (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate is used for serine and methionine biosynthesis for instance .
