产品名称
ARL1 Rabbit Polyclonal Antibody
蛋白名称
ADP-ribosylation factor-like protein 1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=400
Human Swissprot No.
P40616
Human Swissprot Link
https://www.uniprot.org/uniprot/P40616
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=104303
Mouse Swissprot No.
P61211
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P61211/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=64187
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P61212/entry
特异性
This antibody detects endogenous levels of ARL1 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Detected in heart, liver, lung and liver (at protein level). Detected in fetal heart, lung, liver and kidney. Detected in adult heart, placenta, lung, liver, skeletal muscle, kidney and pancreas.
细胞定位
Golgi apparatus membrane ; Peripheral membrane protein ; Cytoplasmic side . Golgi apparatus, trans-Golgi network membrane . Membrane ; Lipid-anchor .
功能
GTP-binding protein that recruits several effectors, such as golgins, arfaptins and Arf-GEFs to the trans-Golgi network, and modulates their functions at the Golgi complex . Plays thereby a role in a wide range of fundamental cellular processes, including cell polarity, innate immunity, or protein secretion mediated by arfaptins, which were shown to play a role in maintaining insulin secretion from pancreatic beta cells .
