产品名称
IRF2BP2 Rabbit Polyclonal Antibody
蛋白名称
Interferon regulatory factor 2-binding protein 2 (IRF-2-binding protein 2) (IRF-2BP2)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=359948
Human Swissprot No.
Q7Z5L9
Human Swissprot Link
https://www.uniprot.org/uniprot/Q7Z5L9
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=270110
Mouse Swissprot No.
E9Q1P8
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/E9Q1P8/entry
特异性
This antibody detects endogenous levels of IRF2BP2 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Acts as a transcriptional corepressor in a IRF2-dependent manner; this repression is not mediated by histone deacetylase activities . Represses the NFAT1-dependent transactivation of NFAT-responsive promoters . Acts as a coactivator of VEGFA expression in cardiac and skeletal muscles . Plays a role in immature B-cell differentiation .
