产品名称
DIO1 Rabbit Polyclonal Antibody
蛋白名称
Type I iodothyronine deiodinase (EC 1.97.1.10) (5DI) (DIOI) (Type 1 DI) (Type-I 5'-deiodinase)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1733
Human Swissprot No.
P49895
Human Swissprot Link
https://www.uniprot.org/uniprot/P49895
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=13370
Mouse Swissprot No.
Q61153
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q61153/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25430
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P24389/entry
特异性
This antibody detects endogenous levels of DIO1 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Endoplasmic reticulum membrane ; Single-pass membrane protein .
功能
Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine). Plays a role in providing a source of plasma T3 by deiodination of T4 in peripheral tissues such as liver and kidney.
