BD-PN1109

PPR1A Rabbit Polyclonal Antibody

常规抗体

PPP1R1A IPP1

Protein phosphatase 1 regulatory subunit 1A (Protein phosphatase inhibitor 1) (I-1) (IPP-1)

WB

Human,Mouse,Rat

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.

5502

Q13522

https://www.uniprot.org/uniprotkb/Q13522/entry

Q9ERT9

http://www.uniprot.org/uniprot/Q9ERT9

P19103

http://www.uniprot.org/uniprot/O54941P19103

Synthesized peptide derived from human protein . at AA range: 40-120

PPR1A Polyclonal Antibody detects endogenous levels of protein.

WB 1:500-2000 ELISA 1:5000-20000

18kD

-20°C/1 year

Polyclonal, Rabbit,IgG

function:Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases.,PTM:Phosphorylation of Thr-35 is required for activity.,similarity:Belongs to the protein phosphatase inhibitor 1 family.,subunit:Interacts with PPP1R15A.,

Brain,Heart,

extracellular space,cytoplasm,

Long-term potentiation;

function:Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases.,PTM:Phosphorylation of Thr-35 is required for activity.,similarity:Belongs to the protein phosphatase inhibitor 1 family.,subunit:Interacts with PPP1R15A.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.