产品名称
HADH Rabbit Polyclonal Antibody
基因名称
HADH HAD HADHSC SCHAD
蛋白名称
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HCDH) (EC 1.1.1.35) (Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase) (Short-chain 3-hydroxyacyl-CoA dehydrogenase)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3033
Human Swissprot No.
Q16836
Human Swissprot Link
https://www.uniprot.org/uniprot/Q16836
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=15107
Mouse Swissprot No.
Q61425
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q61425/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=113965
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q9WVK7/entry
特异性
This antibody detects endogenous levels of HADH at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in liver, kidney, pancreas, heart and skeletal muscle.
细胞定位
Mitochondrion matrix .
功能
Mitochondrial fatty acid beta-oxidation enzyme that catalyzes the third step of the beta-oxidation cycle for medium and short-chain 3-hydroxy fatty acyl-CoAs (C4 to C10) . Plays a role in the control of insulin secretion by inhibiting the activation of glutamate dehydrogenase 1 (GLUD1), an enzyme that has an important role in regulating amino acid-induced insulin secretion (By similarity).