产品名称
LMOD1 Rabbit Polyclonal Antibody
蛋白名称
Leiomodin-1 (64 kDa autoantigen 1D) (64 kDa autoantigen 1D3) (64 kDa autoantigen D1) (Leiomodin, muscle form) (Smooth muscle leiomodin) (SM-Lmod) (Thyroid-associated ophthalmopathy autoantigen)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25802
Human Swissprot No.
P29536
Human Swissprot Link
https://www.uniprot.org/uniprot/P29536
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=93689
Mouse Swissprot No.
Q8BVA4
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BVA4/entry
特异性
This antibody detects endogenous levels of LMOD1 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Detected in lung vascular smooth muscle (at protein level) (PubMed:27144530). Detected in thyroid and extraocular smooth muscle, but not skeletal muscle (PubMed:2026759). Detected in heart, aorta, skeletal muscle, colon, urinary bladder, uterus, stomach, and small intestine (PubMed:11318603).
细胞定位
Cytoplasm, myofibril, sarcomere . Cytoplasm, cytoskeleton . Colocalizes with actin filaments in sarcomeres. .
功能
Required for proper contractility of visceral smooth muscle cells . Mediates nucleation of actin filaments.