产品名称
SNAP29 Rabbit Polyclonal Antibody
蛋白名称
Synaptosomal-associated protein 29 (SNAP-29) (Soluble 29 kDa NSF attachment protein) (Vesicle-membrane fusion protein SNAP-29)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9342
Human Swissprot No.
O95721
Human Swissprot Link
https://www.uniprot.org/uniprot/O95721
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=67474
Mouse Swissprot No.
Q9ERB0
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9ERB0/entry
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Z2P6/entry
特异性
This antibody detects endogenous levels of SNAP29 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Found in brain, heart, kidney, liver, lung, placenta, skeletal muscle, spleen and pancreas.
细胞定位
Cytoplasm . Golgi apparatus membrane ; Peripheral membrane protein . Cytoplasmic vesicle, autophagosome membrane ; Peripheral membrane protein . Cell projection, cilium membrane ; Peripheral membrane protein . Appears to be mostly membrane-bound, probably via interaction with syntaxins, but a significant portion is cytoplasmic. Localizes to the ciliary pocket from where the cilium protrudes. .
功能
SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. SNAP29 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. Plays also a role in ciliogenesis by regulating membrane fusions.
