产品名称
PTPN23 Rabbit Polyclonal Antibody
蛋白名称
Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25930
Human Swissprot No.
Q9H3S7
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9H3S7
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=104831
Mouse Swissprot No.
Q6PB44
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q6PB44/entry
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/O88902/entry
特异性
This antibody detects endogenous levels of PTPN23 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Nucleus. Cytoplasm. Cytoplasmic vesicle. Endosome. Cytoplasm, cytoskeleton, cilium basal body. Early endosome.
功能
Plays a role in sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) via its interaction with the ESCRT-I complex (endosomal sorting complex required for transport I), and possibly also other ESCRT complexes . May act as a negative regulator of Ras-mediated mitogenic activity . Plays a role in ciliogenesis .
