产品名称
QSOX1 Rabbit Polyclonal Antibody
基因名称
QSOX1 QSCN6 UNQ2520/PRO6013
蛋白名称
Sulfhydryl oxidase 1 (hQSOX) (EC 1.8.3.2) (Quiescin Q6)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5768
Human Swissprot No.
O00391
Human Swissprot Link
https://www.uniprot.org/uniprot/O00391
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=104009
Mouse Swissprot No.
Q8BND5
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BND5/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=84491
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q6IUU3/entry
特异性
This antibody detects endogenous levels of QSOX1 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in heart, placenta, lung, liver, skeletal muscle, pancreas and very weakly in brain and kidney.
细胞定位
[Isoform 1]: Golgi apparatus membrane ; Single-pass membrane protein . Secreted . A small proportion is secreted, probably via a proteolytic cleavage that removes the membrane anchor. .; [Isoform 2]: Secreted . Found in the extracellular medium of quiescent cells but is not found in proliferating cells. .
功能
Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide . Plays a role in disulfide bond formation in a variety of extracellular proteins . In fibroblasts, required for normal incorporation of laminin into the extracellular matrix, and thereby for normal cell-cell adhesion and cell migration .
