产品名称
MAGT1 Rabbit Polyclonal Antibody
基因名称
MAGT1 IAG2 PSEC0084 UNQ628/PRO1244
蛋白名称
Magnesium transporter protein 1 (MagT1) (Implantation-associated protein) (IAP)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=84061
Human Swissprot No.
Q9H0U3
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9H0U3
Mouse Swissprot No.
Q9CQY5
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9CQY5/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=116967
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/O35777/entry
特异性
This antibody detects endogenous levels of MAGT1 at Human,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Ubiquitous. Expressed at very low levels in brain, lung and kidney.
细胞定位
Cell membrane ; Multi-pass membrane protein . Endoplasmic reticulum . Endoplasmic reticulum membrane ; Multi-pass membrane protein .
功能
Accessory component of the STT3B-containing form of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains . Involved in N-glycosylation of STT3B-dependent substrates . Specifically required for the glycosylation of a subset of acceptor sites that are near cysteine residues; in this function seems to act redundantly with TUSC3. In its oxidized form proposed to form transient mixed disulfides with a glycoprotein substrate to facilitate access of STT3B to the unmodified acceptor site. Has also oxidoreductase-independent functions in the STT3B-containing OST complex possibly involving substrate recognition. ; May be involved in Mg(2+) transport in epithelial cells.
