产品名称
DHFR Rabbit Polyclonal Antibody
蛋白名称
Dihydrofolate reductase (EC 1.5.1.3)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1719
Human Swissprot No.
P00374
Human Swissprot Link
https://www.uniprot.org/uniprot/P00374
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=13361
Mouse Swissprot No.
P00375
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P00375/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=24312
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q920D2/entry
特异性
This antibody detects endogenous levels of DHFR at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Widely expressed in fetal and adult tissues, including throughout the fetal and adult brains and whole blood. Expression is higher in the adult brain than in the fetal brain.
细胞定位
Mitochondrion . Cytoplasm .
功能
Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA and that of DHFR2.
