产品名称
VAMP2 Rabbit Polyclonal Antibody
蛋白名称
Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6844
Human Swissprot No.
P63027
Human Swissprot Link
https://www.uniprot.org/uniprot/P63027
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=22318
Mouse Swissprot No.
P63044
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P63044/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=24803
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P63045/entry
特异性
This antibody detects endogenous levels of VAMP2 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Nervous system and skeletal muscle.
细胞定位
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Single-pass type IV membrane protein . Cell membrane . Colocalizes with PRKCZ and WDFY2 in intracellular vesicles (PubMed:17313651). .
功能
Involved in the targeting and/or fusion of transport vesicles to their target membrane (By similarity). Major SNARE protein of synaptic vesicles which mediates fusion of synaptic vesicles to release neurotransmitters. Essential for fast vesicular exocytosis and activity-dependent neurotransmitter release as well as fast endocytosis that mediates rapid reuse of synaptic vesicles (By similarity) . Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1.
