产品名称
COQ7 Rabbit Polyclonal Antibody
蛋白名称
Ubiquinone biosynthesis protein COQ7 homolog (Coenzyme Q biosynthesis protein 7 homolog) (Timing protein clk-1 homolog)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10229
Human Swissprot No.
Q99807
Human Swissprot Link
https://www.uniprot.org/uniprot/Q99807
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=12850
Mouse Swissprot No.
P97478
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P97478/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25249
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q63619/entry
特异性
This antibody detects endogenous levels of COQ7 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed dominantly in heart and skeletal muscle.
细胞定位
Mitochondrion inner membrane ; Peripheral membrane protein ; Matrix side . Mitochondrion . Nucleus . Chromosome .
功能
Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis (By similarity). Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides (By similarity). Involved in lifespan determination in a ubiquinone-independent manner (By similarity). Plays a role in modulating mitochondrial stress responses, acting in the nucleus, perhaps via regulating gene expression, independent of its characterized mitochondrial function in ubiquinone biosynthesis .