产品名称
MLXIP Rabbit Polyclonal Antibody
基因名称
MLXIP BHLHE36 KIAA0867 MIR MONDOA
蛋白名称
MLX-interacting protein (Class E basic helix-loop-helix protein 36) (bHLHe36) (Transcriptional activator MondoA)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=22877
Human Swissprot No.
Q9HAP2
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9HAP2
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=208104
Mouse Swissprot No.
Q2VPU4
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q2VPU4/entry
特异性
This antibody detects endogenous levels of MLXIP at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Widely expressed in adult tissues. Most abundant in skeletal muscle.
细胞定位
Cytoplasm . Nucleus . Mitochondrion outer membrane . Predominantly cytoplasmic but shuttles between cytoplasm and nucleus when associated with MLX. Also associates with the outer mitochondrial membrane and may shuttle between the outer mitochondrial membrane and the nucleus. .
功能
Binds DNA as a heterodimer with MLX and activates transcription. Binds to the canonical E box sequence 5'-CACGTG-3'. Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation.
