产品名称
SELS Rabbit Polyclonal Antibody
基因名称
VIMP SELS AD-015 SBBI8
蛋白名称
Selenoprotein S (SelS) (VCP-interacting membrane protein)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=55829
Human Swissprot No.
Q9BQE4
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9BQE4
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=109815
Mouse Swissprot No.
Q9BCZ4
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9BCZ4/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=286900
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q8VHV8/entry
特异性
This antibody detects endogenous levels of SELS at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Endoplasmic reticulum membrane; Single-pass membrane protein. Cytoplasm .
功能
Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Probably acts by serving as a linker between DERL1, which mediates the retrotranslocation of misfolded proteins into the cytosol, and the ATPase complex VCP, which mediates the translocation and ubiquitination.
