产品名称
CAPG Rabbit Polyclonal Antibody
蛋白名称
Macrophage-capping protein (Actin regulatory protein CAP-G)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=822
Human Swissprot No.
P40121
Human Swissprot Link
https://www.uniprot.org/uniprot/P40121
Mouse Swissprot No.
P24452
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P24452/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=297339
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q6AYC4/entry
特异性
This antibody detects endogenous levels of CAPG at Human,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Macrophages and macrophage-like cells.
细胞定位
Nucleus . Cytoplasm . Melanosome . Cell projection, lamellipodium . Cell projection, ruffle . In macrophages, may be predominantly cytoplasmic. Nuclear localization was observed in fibroblasts. In macrophages, present at the membrane-cytoplasm interface. In activated macrophages, concentrated in the ruffles of the leading lamellipodia. .
功能
Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA.
