产品名称
RHOC Rabbit Polyclonal Antibody
蛋白名称
Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=389
Human Swissprot No.
P08134
Human Swissprot Link
https://www.uniprot.org/uniprot/P08134
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=11853
Mouse Swissprot No.
Q62159
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q62159/entry
特异性
This antibody detects endogenous levels of RHOC at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Cell membrane ; Lipid-anchor ; Cytoplasmic side . Cleavage furrow . Translocates to the equatorial region before furrow formation in a ECT2-dependent manner.
功能
Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Regulates apical junction formation in bronchial epithelial cells.
