产品名称
SLC4A4 Rabbit Polyclonal Antibody
基因名称
SLC4A4 NBC NBC1 NBCE1
蛋白名称
Electrogenic sodium bicarbonate cotransporter 1 (Sodium bicarbonate cotransporter) (Na(+)/HCO3(-) cotransporter) (Solute carrier family 4 member 4) (kNBC1)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8671
Human Swissprot No.
Q9Y6R1
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9Y6R1
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=54403
Mouse Swissprot No.
O88343
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/O88343/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=84484
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q9JI66/entry
特异性
This antibody detects endogenous levels of SLC4A4 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Isoform 1 is expressed in pancreas and to a lower extent in heart, skeletal muscle, liver, parotid salivary glands, prostate, colon, stomach, thyroid, brain and spinal chord. Corneal endothelium cells express only isoform 1 (at protein level). Isoform 2 is specifically expressed in kidney at the level of proximal tubules.
细胞定位
Basolateral cell membrane ; Multi-pass membrane protein .
功能
Electrogenic sodium/bicarbonate cotransporter with a Na(+):HCO3(-) stoichiometry varying from 1:2 to 1:3. May regulate bicarbonate influx/efflux at the basolateral membrane of cells and regulate intracellular pH. ; [Isoform 2]: May have a higher activity than isoform 1.
