产品名称
PLDN Rabbit Polyclonal Antibody
蛋白名称
Pallidin (Pallid protein homolog) (Syntaxin 13-interacting protein)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=26258
Human Swissprot No.
Q9UL45
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9UL45
特异性
This antibody detects endogenous levels of PLDN at Human
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Cytoplasm . Membrane ; Peripheral membrane protein . It can exist as a soluble protein as well as a peripheral membrane protein (PubMed:12019270). .
功能
Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particularly in the vesicle-docking and fusion process.
