产品名称
PRKCDBP Rabbit Polyclonal Antibody
蛋白名称
Protein kinase C delta-binding protein (Cavin-3) (Serum deprivation response factor-related gene product that binds to C-kinase) (hSRBC)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=112464
Human Swissprot No.
Q969G5
Human Swissprot Link
https://www.uniprot.org/uniprot/Q969G5
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=109042
Mouse Swissprot No.
Q91VJ2
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q91VJ2/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=85332
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Z1H9/entry
特异性
This antibody detects endogenous levels of PRKCDBP at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Skeletal muscle, liver, stomach, lung, kidney and heart (at protein level). Strongly expressed in mammary and epithelial cells.
细胞定位
Cytoplasm . Membrane, caveola . Cytoplasm, cytosol . Localizes in the caveolae in a caveolin-dependent manner. .
功能
Regulates the traffic and/or budding of caveolae . Plays a role in caveola formation in a tissue-specific manner. Required for the formation of caveolae in smooth muscle but not in the lung and heart endothelial cells. Regulates the equilibrium between cell surface-associated and cell surface-dissociated caveolae by promoting the rapid release of caveolae from the cell surface. Plays a role in the regulation of the circadian clock. Modulates the period length and phase of circadian gene expression and also regulates expression and interaction of the core clock components PER1/2 and CRY1/2 (By similarity).
