产品名称
GNMT Rabbit Polyclonal Antibody
蛋白名称
Glycine N-methyltransferase (EC 2.1.1.20)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=27232
Human Swissprot No.
Q14749
Human Swissprot Link
https://www.uniprot.org/uniprot/Q14749
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=14711
Mouse Swissprot No.
Q9QXF8
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9QXF8/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25134
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P13255/entry
特异性
This antibody detects endogenous levels of GNMT at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed only in liver, pancreas, and prostate.
功能
Catalyzes the methylation of glycine by using S-adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy), a reaction regulated by the binding of 5-methyltetrahydrofolate. Plays an important role in the regulation of methyl group metabolism by regulating the ratio between S-adenosyl-L-methionine and S-adenosyl-L-homocysteine.