产品名称
PRD10 Rabbit Polyclonal Antibody
基因名称
PRDM10 KIAA1231 PFM7 TRIS
蛋白名称
PR domain zinc finger protein 10 (PR domain-containing protein 10) (Tristanin)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9NQV6
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9NQV6/entry
Mouse Swissprot No.
Q3UTQ7
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q3UTQ7
免疫原
Synthesized peptide derived from human protein . at AA range: 280-360
特异性
PRD10 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a transcription factor that contains C2H2-type zinc-fingers. It also contains a positive regulatory domain, which has been found in several other zinc-finger transcription factors including those involved in B cell differentiation and tumor suppression. Studies of the mouse counterpart suggest that this protein may be involved in the development of the central nerve system (CNS), as well as in the pathogenesis of neuronal storage disease. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008],
组织表达
Brain,Colon mucosa,Uterus,
功能
domain:The SET domain is degenerated, suggesting that it has lost mehtyltransferase activity.,function:May be involved in transcriptional regulation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 SET domain.,similarity:Contains 10 C2H2-type zinc fingers.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
