产品名称
MKS1 Rabbit Polyclonal Antibody
蛋白名称
Meckel syndrome type 1 protein
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=54903
Human Swissprot No.
Q9NXB0
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9NXB0
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=380718
Mouse Swissprot No.
Q5SW45
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q5SW45/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=287612
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q499Q5/entry
特异性
This antibody detects endogenous levels of MKS1 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Localizes at the transition zone, a region between the basal body and the ciliary axoneme. .
功能
Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involved in centrosome migration to the apical cell surface during early ciliogenesis. Required for ciliary structure and function, including a role in regulating length and appropriate number through modulating centrosome duplication. Required for cell branching morphology.
