产品名称
ATP4B Rabbit Polyclonal Antibody
蛋白名称
Potassium-transporting ATPase subunit beta (Gastric H(+)/K(+) ATPase subunit beta) (Proton pump beta chain)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P51164
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P51164/entry
Mouse Swissprot No.
P50992
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P50992
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P18598
免疫原
Synthesized peptide derived from human protein . at AA range: 160-240
特异性
ATP4B Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene belongs to a family of P-type cation-transporting ATPases. The gastric H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This enzyme is a proton pump that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for gastric acid secretion. This gene encodes the beta subunit of the gastric H+, K+-ATPase. [provided by RefSeq, Jul 2008],
细胞定位
Apical cell membrane ; Single-pass type II membrane protein . Cell membrane ; Single-pass type II membrane protein . Localized in the apical canalicular membrane of parietal cells. .
信号通路
Oxidative phosphorylation;
功能
similarity:Belongs to the X(+)/potassium ATPases subunit beta family.,subunit:Composed of two subunits: alpha (catalytic) and beta.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.