产品名称
RAB27B Rabbit Polyclonal Antibody
蛋白名称
Ras-related protein Rab-27B (C25KG)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5874
Human Swissprot No.
O00194
Human Swissprot Link
https://www.uniprot.org/uniprot/O00194
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=80718
Mouse Swissprot No.
Q99P58
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q99P58/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=84590
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q99P74/entry
特异性
This antibody detects endogenous levels of RAB27B at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed primarily in testis.
细胞定位
Membrane; Lipid-anchor. Late endosome .
功能
Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion . Plays a role in NTRK2/TRKB axonal anterograde transport by facilitating the association of NTRK2/TRKB with KLC1 . May be involved in targeting uroplakins to urothelial apical membranes (By similarity).
