产品名称
CAPRIN1 Rabbit Polyclonal Antibody
基因名称
CAPRIN1 GPIAP1 GPIP137 M11S1 RNG105
蛋白名称
Caprin-1 (Cell cycle-associated protein 1) (Cytoplasmic activation- and proliferation-associated protein 1) (GPI-anchored membrane protein 1) (GPI-anchored protein p137) (GPI-p137) (p137GPI) (Membrane component chromosome 11 surface marker 1) (RNA granule protein 105)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4076
Human Swissprot No.
Q14444
Human Swissprot Link
https://www.uniprot.org/uniprot/Q14444
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=53872
Mouse Swissprot No.
Q60865
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q60865/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=362173
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q5M9G3/entry
特异性
This antibody detects endogenous levels of CAPRIN1 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Cytoplasm, cytosol . Cell projection, dendrite . Cell projection, lamellipodium . Associated with RNA granules. At the leading edge of migrating fibroblasts, colocalizes with DDX3X (PubMed:28733330). .
功能
May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. Binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, directly binds to several mRNAs associated with RNA granules, including BDNF, CAMK2A, CREB1, MAP2, NTRK2 mRNAs, as well as to GRIN1 and KPNB1 mRNAs, but not to rRNAs.
