产品名称
TOM70 Rabbit Polyclonal Antibody
基因名称
TOMM70A KIAA0719 TOM70
蛋白名称
Mitochondrial import receptor subunit TOM70 (Mitochondrial precursor proteins import receptor) (Translocase of outer membrane 70 kDa subunit)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9868
Human Swissprot No.
O94826
Human Swissprot Link
https://www.uniprot.org/uniprot/O94826
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=28185
Mouse Swissprot No.
Q9CZW5
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9CZW5/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=304017
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q75Q39/entry
特异性
This antibody detects endogenous levels of TOM70 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Mitochondrion outer membrane ; Single-pass membrane protein .
功能
Acts as receptor of the preprotein translocase complex of the outer mitochondrial membrane (TOM complex). Recognizes and mediates the translocation of mitochondrial preproteins from the cytosol into the mitochondria in a chaperone dependent manner . Mediates TBK1 and IRF3 activation induced by MAVS in response to Sendai virus infection and promotes host antiviral responses during virus infection . Upon Sendai virus infection, recruits HSP90AA1:IRF3:BAX in mitochondrion and the complex induces apoptosis .
